Mandarin Orchard Singapore (previously Mandarin Singapore and Meritus Mandarin Singapore) managed by Meritus Hotels & Resorts (Chinese: 文华大酒店), is a five-star hotel located at 333 Orchard Road in Singapore. Opened in 1971 and occupying a single 36-story block, it became a landmark for the Orchard Road area when the second block, standing at 40 stories and 173 metres high, became the tallest development in the area when it opened in 1973. Designed by Stanley T.S. Leong, it currently has over 1,051 rooms and 32 suites, two exclusive Club lounges and two Presidential Suites. In 1980, the South Tower was extended with the help of Lee Sian Teck Chartered Architects. The Grand Tower was upgraded again in 2003 at a cost of S$52 million. At the top of the South Tower is the Mandarin Club Lounge, while the taller tower has the Top of the 'M', the tallest revolving restaurant in Singapore.

As of 2011 the 2 tower blocks holds a total of 1200 rooms.The hotel underwent a major S$200 millionrenovations in 2009 which saw the previous hotel lobby on the first floor and the lower few levels of the hotel revamped to become a shopping arcade known as Mandarin Gallery. The hotel lobby itself was relocated to level 5 besides the swimming pool.

The hotel specifically targets at the business traveler market, and is thus a popular venue for meetings and conferences with facilities seating up to 1200 people. Voted as one of the World’s Best Places to Stay in the 2004 Gold List of Condé Nast Traveler and into the list of The World’s Top 75 Hotels in 2003 of Institutional Investor, it is the flagship hotel of Meritus Hotels and Resorts.

The Chatterbox restaurant at the hotel is well-known for its award winning Hainanese chicken rice. In 2007, the originator of the dish, Steven Low, was laid off after 31 years of service; he promptly opened his own restaurant, serving the same dish at a quarter of the price. The hotel also has a recently renovated shopping complex, Mandarin Gallery (Chinese: 文华购物廊), which has branded boutiques such as Montblanc (pens), Emporio Armani, Marc by Marc Jacobs, D&G, Vertu, Just Cavalli and Mauboussin, as well as restaurants such as Ippudo.

Part of the Meritus Hotels & Resorts, Mandarin Orchard Singapore has a sister hotel, Marina Mandarin Singapore, located at the Marina Bay.