The Hôtel Biron is an hôtel particulier in the rue de Varenne, Paris VIIème, that was built by Jacques Gabriel and his associate designer Jean Aubert, in 1728-31 Since 1919 it has housed the Musée Auguste Rodin.

The hôtel was built for a peruke-maker, Abraham Peyrenc de Moras, who had speculated successfully in the ill-fated paper money schemes of John Law that had ruined many, at a time when the Faubourg Saint-Germain was still suburban in character. His house, the most superb in the neighborhood, was built as a free-standing structure, not built entre cour et jardin, "between entrance court and garden" with party walls against adjoining buildings, as hôtels in more densely-built quarters of Paris have traditionally been built since the seventeenth century. The house is still surrounded by three hectares/7.3 acres of grounds. The house had boiseries carved in the full-blown rococo manner and has two elliptical salons that form attached pavilions at the corners of the garden front. There were sixteen medallions or overdoor paintings by François Lemoyne, premier peintre du roi, enframed in the panelling. The Hôtel Peyrenc de Moras, as it then was, was completed in 1731, just a year before Peyrenc's death. His widow sold the house to the duchesse du Maine, who had married a natural son of Louis XIV; she took possession in January 1737 (Kimball loc. cit.) and made some minor changes. Upon the death of the duchess in 1753, the mansion became the property of the maréchal de Biron, hero of Fontenoy, whose name it has carried. A plan of the house and gardens as they were in 1752 shows the deep terrace at the rear with a few wide bowed steps that led to matching parterres containing shaped compartments set in gravel and surrounded by shrubs tightly clipped in cones which flanked a wide central gravel walk. To the left of the deep cour d'honneur and entered from it, neatly-clipped cabinets de verdure —small open-air rooms and recesses in fanciful shapes, connected by short galleries— were cut into solid greenery. On the right hand of the court was a subsidiary stable courtyard. Soon the gardens were swept away by the duc de Biron, in favour of a miniature park à l'Anglaise, achieved with trelliswork. When the "comte du Nord", the future Paul I of Russia, and his countess, who were travelling technically incognito for pleasure, visited Paris in 1782, they toured the garden, "which is one of the wonders of Paris, admiring the beauty of the flowers and the variety of the borders. They walked among the flower beds and the shrubberies, marvelling at the boldness and elegance of the trellis work forming gateways, arcades, grottoes, domes, Chinese pavilions..."

By the end of the eighteenth century, the faubourg was becoming demodé, with the westward development of fashionable Paris on the Rive Droite. The duc de Biron's heir, Armand Louis de Gontaut, duc de Lauzun, was guillotined in 1793. During Napoleon's reign, the Hôtel de Biron was the seat of the Papal legate and then of the Russian ambassador. In 1820 it was given to the Société du Sacré-Coeur de Jésus, whose Dames du Sacre-Coeur, dedicated to the education of young women, converted the hotel into a boarding school for girls from aristocratic families, and stripped the house of all luxuries, mirrors and boiseries and added a chapel.

Under the 1905 French law on the separation of Church and State, however, the school was forced to close. The house was subdivided into lodgings, and plans were afoot to demolish the mansion entirely and replace it by a block of flats. Auguste Rodin rented several rooms on the ground floor in which to store his sculptures. The rooms became his studio; there he worked and entertained friends among the overgrown gardens.

In 1909, Rodin, at the height of his fame, began to agitate for the Hôtel Biron to become a museum of his work. He made a bequest of his property, his archives and the contents of his studio at the time of his death, and the French government accepted in 1916. The museum opened in 1919.

Since World War II, the Musée Rodin has been able to buy back boiseries and decorative paintings formerly in the house, which were stripped out by the Dames du Sacre-Coeur and sold. Recently the museum was able to buy two of Lemoyne's overdoors, Venus Showing Cupid the Ardour of his Arrows and the Labours of Penelope, and restore them to their original positions.